World number three, Roger Federer, will play Denis Istomin in his first round match of the 2019 Australian Open.
Istomin caused a big upset two years ago, when he eliminated world number one, Novak Djokovic, in the second round of the event.
Britain’s Andy Murray, who is currently ranked 230th by the ATP, will face Bautista Agut, who is ranked 22nd in the world, as he continues his comeback from a hip surgery.
In other first round fixtures, Kyle Edmund, who reached the semi-finals last year, will meet former Wimbledon finalist, Tomas Berdych.
British number one women player and 2016 semi-finalist, Johanna Konta, will battle home player, Ajla Tomljanovic.
Djokovic will face a qualifier in the first round, in which it could potentially be France’s Jo-Wilfried Tsonga in the second round.
Serena Williams faces Germany’s Tatjana Maria in her first match, since losing the US Open final in controversial circumstances to Japan’s Naomi Osaka.
Australia’s Nick Kyrgios, who is not seeded in the men’s draw, will face Canada’s Milos Raonic.
Defending champion in the women’s category, Caroline Wozniacki, who won her first Grand Slam title last year, will start her defence against Belgium’s Alison van Uytvanck.
Top seed, Simona Halep, has been given a chance to take revenge on Estonia’s Kaia Kanepi, who eliminated her in the first round of the US Open last August.
The draws were conducted by Australian tennis legend, Rod Laver and tournament director, Craig Tiley, at Melbourne Park on Thursday.
The singles champions will take home $2.5million each.
The tournament will take place between January 14 and 27.